To name one whose method I really like, Lenovo (formerly IBM Thinkpad)... When set up properly, the HDD will hardware-lock to the laptop's bios (the HDD controller board checks the CMOS serial # and shuts down if it doesn't match a stored value), preventing the successful extraction of data by simply moving the drive to another machine. If that's not enough, it also encrypts the drive using a cypher that is also encrypted, stored in the controller board; that is, the password is not the cypher in any way, but merely decrypts the stored cypher, allowing access to the rest of the encrypted data. If the wrong password is given X number of times, the cypher is deleted, rendering the data unrecoverable. All of this functionality is standard.
THAT SAID....

You aren't protecting your data from anyone who will go to extraordinary lengths to get it; that would require some creative thinking, and some thermite. You just want to keep the casual thief out of your business.